Endocrine Abstracts

Materials and methods: A survey was 95 people (45 people with diabetes mellitus type 1, 50 people with diabetes mellitus type 2). The age of examined patients 39.12±3.8. The disease duration ranged from 6 to 20 years. Level of biochemical indicators – normal limits. Condition of mineral density of a bone tissue it was estimated by method of a dual-energy X-ray absorptiometry (DEXA). The analysis of DEXA researches showed that change of mineral density of a bone tissu...

A previously fit and well 49-year-old gentleman presented to hospital with vomiting and myalgia. Three weeks previously he had been admitted with acute pancreatitis, but no cause was found. An incidental hypercalcaemia was also noted at that time. He had lost approximately two stone in weight in the previous three months and had become more short of breath on exertion. He had a strong family history for type I diabetes mellitus, but otherwise there was no significant history.<...

Introduction: Vitamin D deficiency is increasingly recognised as an important cause of neonatal hypocalcaemia. In this case report, we discuss the impact of co-existing vitamin D deficiency on the diagnostic process in a preterm infant who had refractory hypocalcaemia due to hypoparathyroidism resulting from a homozygous GCM2 mutation.Case report: A 33-week gestation male infant of Pakistani extraction was found to be profoundly hypocalcaemic with seizur...

Neonatal thyrotoxicosis (NT) is a rare condition caused by the transplacental passage of maternal thyroid-stimulating antibodies from mothers with active Graves’ disease or a past history of the condition. We suspected that there were wide differences in the way that babies at risk of NT were managed in our locality and undertook a survey to establish the local approach to this clinical problem.Method: The lead clinician who was considered most like...

Case History: We present a case of a 24 year old music teacher and who attended our medical assessment unit. The gentleman described a twelve day history of neck pain, malaise, and odynophagia having received treatment one month previously for a PVL positive Staphylococcus aureus (PVLSA) lip abscess for which he did not complete eradication therapy. He described associated difficulty swallowing, rigors, vomiting and weight loss. On examination he had a tender, hot goi...

Yu Pei and Sanjiv Risal are joint first authors. Elisabet Stener-Victorin and Qiaolin Deng are joint corresponding authors. Polycystic ovary syndrome (PCOS) affects around 15% of women of reproductive age and the key feature of the syndrome is hyperandrogenism. To understand the complex pathophysiology of PCOS, more than 30 PCOS-like animal models have been developed to mimic certain pathophysiological features. So far, not much is known about the common and unique molecular a...

A 28 year old man with a background of hypothyroidism presented to hospital following a collapse. He had a one week history of unrelenting vomiting with malaise. On examination, he appeared dehydrated and was profoundly hypotensive with a blood pressure of 56/25 mm Hg. General examination was otherwise unremarkable. The blood tests demonstrated acute kidney injury with serum creatinine 227 mmol/L and hyponatraemia with serum sodium 130 mmol/L. His potassium was within normal l...

Aim: Promoting cohesion, community and knowledge of diabetes through the co-production of a video exploring the social and clinical impact of attending a residential activity camp for children and families living with type 1 diabetesMethod: From our knowledge of attending previous diabetes camps, the video will begin by highlighting the background and motivation behind the study, emphasising the limited understanding of ...

Aim: Camps offer valuable opportunities for creating a supportive environment of like-minded people with similar experiences of living with diabetes, thereby promoting self-efficacy, wellbeing and a healthy life style. In the midst of a post-Covid cost of living crisis, finance was identified as a major obstacle for families wishing to attend residential diabetes camps. A sustainable strategy, supported by co-production with young people, was needed to facilit...

Case history: A 74 year old female was treated for hyperthyroidism of uncertain aetiology by her general practitioner. Carbimazole had been continued for 15 years - current dose 5 mg daily. Following referral to endocrine outpatients, consideration was given to stopping carbimazole as this treatment was possibly no longer required, although a small risk of relapse was accepted. Prior to stopping carbimazole, Free T4 - 10.5 pmol/l (7.5–21.1), TSH - 0.61 mU/l (0.35–4.7...